Tranexamic acid (TXA)

From Guide to YKHC Medical Practices

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DOSING

2 grams slow IV/IO push within 3 hours of injury.[1]

DISCUSSION

In the fall of 2020 the United States Department of Defense (DOD) Committed on Tactical Combat Casualty Care (CoTCCC)[2] updated the Tactical Combat Casualty Care (TCCC) guidelines to specify TXA dosing of 2 grams slow IV/IO push.[3]

Trauma involving life-threatening hemorrhage in the YK Delta, particularly when managed in village clinics, occurs in a context with substantial similarities to the military battlefield. For example: blood supplies are limited (or nonexistant), transport times are long, the number of persons carrying for the patient are limited, etc.

REFERENCES

  1. Drew B, Auten JD, Cap AP, et al. The Use of Tranexamic Acid in Tactical Combat Casualty Care: TCCC Proposed Change 20-02. J Spec Oper Med. 2020;20(3):36-43. https://www.jsomonline.org/AllArticles.php#Article1037
  2. Committee on Tactical Combat Casualty Care (CoTCCC) - Joint Trauma System. Accessed November 23, 2021. https://jts.amedd.army.mil/index.cfm/committees/cotccc
  3. TCCC Guidelines. Deployed Medicine. Published November 5, 2020. Accessed November 23, 2021. eBook PDF