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[[File:PB_CSF_pharmacokinetics_01.PNG|right|thumb|500px|'''Fig-1'''.  Phenobarbital brain concentration versus time after a rapid bolus injection.  Y-axis is fractional concentration compared to the initial serum concentration (which has been removed for clarity).  Adapted from Paulson 1982<ref>Paulson OB, Györy A, Hertz MM. Blood-brain barrier transfer and cerebral uptake of antiepileptic drugs. Clin Pharmacol Ther. 1982;32(4):466-477. doi:10.1038/clpt.1982.190</ref>]]
[[File:PB_CSF_pharmacokinetics_01.PNG|right|thumb|400px|'''Fig-1.  Phenobarbital brain concentration versus time after a rapid bolus injection'''.  Y-axis is fractional concentration compared to the initial serum concentration (which has been removed for clarity).  Adapted from Paulson 1982<ref>Paulson OB, Györy A, Hertz MM. Blood-brain barrier transfer and cerebral uptake of antiepileptic drugs. Clin Pharmacol Ther. 1982;32(4):466-477. doi:10.1038/clpt.1982.190</ref>]]
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Revision as of 06:08, 31 August 2019

Introduction

Section One

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Fig-1. Phenobarbital brain concentration versus time after a rapid bolus injection. Y-axis is fractional concentration compared to the initial serum concentration (which has been removed for clarity). Adapted from Paulson 1982[1]

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  1. Paulson OB, Györy A, Hertz MM. Blood-brain barrier transfer and cerebral uptake of antiepileptic drugs. Clin Pharmacol Ther. 1982;32(4):466-477. doi:10.1038/clpt.1982.190